1996/08/01 by M. Kanda, Tatsuya Mima, T. Mima +11 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Epilepsy research and treatment #Ion channel regulation and function #Psychosomatic Disorders and Their Treatments
paper · doi:10.1111/j.1600-0404.1996.tb07043.x
crossref issued 1996/08/01 · crossref published 1996/08/01 · crossref published-print 1996/08/01 · openalex publication_date 1996/08/01 · crossref created 2009/01/29 · crossref deposited 2022/12/20 · openalex created_date 2025/10/10 · crossref indexed 2026/08/04 · openalex updated_date 2026/08/04
In 6 patients with Wallenberg's syndrome who showed a dissociated loss of pain sense, we recorded pain-related somatosensory evoked potentials following CO2 laser stimulation of the hand dorsum (pain SEPs). Two components, N2 and P2, were recorded by stimulation of the unaffected hand, whereas on the affected side they were absent or decreased in proportion to the severity of hypalgesia which was evaluated by both needle test and CO2 laser stimulation. Latency of either component, if appeared, was longer in the affected hand stimulation than that in the unaffected one. In contrast, N20 of the conventional electrically-stimulated SEPs (electric SEPs) showed no difference between the two sides. It is concluded that, unlike other electrophysiological methods, pain SEPs following CO2 laser stimulation can quantitatively evaluate functional impairment of the spinothalamic tract in Wallenberg's syndrome.