B/N-doped carbon nano-onions as nanocarriers for targeted breast cancer therapy

2025/01/01 by Hugh Mohan, Iris C. Salaroglio, Michał Bartkowski +7 · 1 voice · 1 citation
Chemistry · Engineering · Materials Science · #Carbon Nanotubes in Composites #Fullerene Chemistry and Applications #Graphene and Nanomaterials Applications

paper · pdf · doi:10.1039/d4nr04990j

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

π-π stacking interactions. The HA-DMPE/BN-CNO/DOX system enhances the uptake and anticancer effects of DOX in MDA-MB-468 and MDA-MB-231 TNBC cells whilst reducing the cardiotoxicity of DOX in AC-16 human cardiomyocytes.

Citations

• Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management

Cited by

• Advances in nanomedicine: from design and formulation to regenerative application and theranostics

Discussions

• Engineered B/N-doped carbon nano-onions coated with a hyaluronic acid targeting agent carry doxorubicin to triple-negative breast cancer cells, enhancing efficacy while mitigating cardiotoxicity. Rea [bsky, 0 points, 0 comments]

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