Caring for Adult Patients With Sepsis

2026/03/26 by Christopher W. Seymour, Kirsten Bibbins-Domingo, Jason T. Alexander · 1 voice
Medicine · #Hemodynamic Monitoring and Therapy #Nosocomial Infections in ICU #Sepsis Diagnosis and Treatment

paper · doi:10.1001/jama.2026.3793

openalex publication_date 2026/03/26 · openalex created_date 2026/03/27 · openalex updated_date 2026/07/28

Abstract

This JAMA Clinical Guidelines Synopsis summarizes the newly released Surviving Sepsis Campaign guidelines from ESICM and SCCM detailing treatment recommendations for adults with sepsis, including antimicrobial therapy and management of fluids.

Discussions

• 🚨 Sepsis guidelines updated (SSC 2026) Key takeaways: ⚡ Early antibiotics (ASAP—ideally ≤1 hr) 🔽 De-escalate when cultures return 🚫 Avoid routine empiric antifungals 💧 30 mL/kg fluids (with nuanc [bsky, 0 points, 0 comments]

Related

• Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021
• Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
• Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026
• Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021
• Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016