Brønsted acid-catalyzed synthesis of trifluoromethylated azulenes via cyclization of 1-phenyl-2-CF 3 -1,3-enynes

2025/12/24 by Wuding Sun, Jimin Yang, Kai Di +7 · 1 voice
Pharmacology, Toxicology and Pharmaceutics · Chemistry · #Fluorine in Organic Chemistry #Synthesis and Characterization of Pyrroles #Inorganic Fluorides and Related Compounds

paper · doi:10.1039/d5qo01617g

openalex created_date 2025/12/24 · openalex publication_date 2025/12/24 · openalex updated_date 2026/07/22

Abstract

Brønsted acid-catalyzed annulation provides a mild, metal-free route to valuable trifluoromethylated azulenes rapidly.

Discussions

• Research article by Yuhan Zhou's team. #DLUT Authors report a simple, Brønsted acid-catalyzed, intramolecular annulation of 1-phenyl-2-CF3-1,3-enynes for the efficient construction of valuable trifl [bsky, 0 points, 0 comments]

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