2023/12/11 by Katharine Hopkins, Annarita Antelmi, Jakob Dahlin +5 · 2 citations
Medicine · #Contact Dermatitis and Allergies #Fibromyalgia and Chronic Fatigue Syndrome Research #Musculoskeletal pain and rehabilitation
paper · pdf · doi:10.2340/actadv.v103.22336
crossref issued 2023/12/11 · crossref published 2023/12/11 · crossref published-online 2023/12/11 · openalex publication_date 2023/12/11 · crossref created 2023/12/11 · crossref deposited 2023/12/11 · openalex created_date 2025/10/10 · crossref indexed 2026/08/01 · openalex updated_date 2026/08/01
Fibromyalgia is a common chronic pain condition. Rates of contact allergy in individuals with fibromyalgia have not been widely studied. Systemic contact allergy can present with muscle and joint pain and general malaise. The aim of this study is to investigate contact allergy rates in individuals with fibromyalgia to the sensitizers in an extended dental series and compare with control groups. Contact allergy to gold was significantly more common in the fibromyalgia group than the dermatitis control group. When corrected for patch test system, contact allergy to gold was significantly more common in the fibromyalgia group than the dental control group. Contact allergy to hydroxyethyl methacrylate and grouped acrylates and methacrylates was significantly more common in the fibromyalgia group than the dental control group. In conclusion, individuals with fibromyalgia may have a propensity to sensitization to gold, either via an increased exposure or an alteration in the oral environment. Gold is also implicated in systemic contact dermatitis and may be a factor in elicitation of symptoms in individuals with fibromyalgia. Acrylate allergy is also common in the fibromyalgia population and may be a consequence of occupational exposure or dental treatment.