2022/12/30 by Burhan Kocyigit, Burhan Fatih Koçyiğit, Ahmet Akyol
Medicine · #Fibromyalgia and Chronic Fatigue Syndrome Research #Musculoskeletal pain and rehabilitation
paper · pdf · doi:10.5114/reum.2022.123671
crossref issued 2022/12/30 · crossref published 2022/12/30 · crossref published-online 2022/12/30 · openalex publication_date 2022/12/30 · crossref created 2023/01/11 · crossref deposited 2023/01/27 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31
Fibromyalgia syndrome (FMS) profoundly impacts patients' quality of life with its symptoms and clinical signs. Fibromyalgia syndrome impairs daily living activities, reduces work efficiency and raises health-related costs. Although the prevalence rates vary depending on geographical location and diagnostic criteria, it is a common disorder worldwide. Females have a higher prevalence of fibromyalgia syndrome, with varied rates, and there is an increase in prevalence rates with age. Although its etiopathogenesis has not been fully elucidated, various hypotheses have been proposed that central sensitization is at the core of the process. Fibromyalgia syndrome diagnostic approaches have advanced significantly over time, moving away from pain assessments alone and emphasizing multiple clinical signs of FMS. This condition has raised physicians' and researchers' awareness of non-pain symptoms. Considering the complicated etiopathogenesis of fibromyalgia syndrome, diverse pathways connected with symptoms, and multiple clinical presentations, it becomes clear that drug and non-drug treatments should be chosen in combination.