Photocatalytic precision editing of amino acid residues: advances, mechanisms, and future directions

2026/01/01 by C. Ju, Ruiping Han, Jun Li +2 · 1 voice
Chemistry · Biochemistry, Genetics and Molecular Biology · #Radical Photochemical Reactions #Click Chemistry and Applications #Chemical Synthesis and Analysis

paper · doi:10.1039/d6qo00346j

openalex publication_date 2026/01/01 · openalex created_date 2026/04/03 · openalex updated_date 2026/06/11

Abstract

This review covers recent advances in visible-light-driven strategies for the mild and precise modification of amino acids, enabling the creation of peptide bioconjugates and the emulation of post-translational modifications.

Citations

• Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
• Aminoalkyl radicals as halogen-atom transfer agents for activation of alkyl and aryl halides
• Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds
• Late-stage C–H functionalization offers new opportunities in drug discovery
• Photoredox-Catalyzed C–H Functionalization Reactions
• Photocatalytic Late-Stage C–H Functionalization

Discussions

• 🔔 Hot article by Teck-Peng Loh, Peizhong Xie 𝘦𝘵 𝘢𝘭. Photocatalytic precision editing of amino acid residues: advances, mechanisms, and future directions 🔗 doi.org/10.1039/D6QO... #Photocataly [bsky, 0 points, 0 comments]

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