2026/05/01 by Dishang Bhavsar, Viral Bhanvdiya, Kajal Chaudhary +3 · 1 voice
Medicine · #Autopsy Techniques and Outcomes #Infectious Disease Case Reports and Treatments #Pediatric Urology and Nephrology Studies
paper · doi:10.21276/apalm.3800
openalex publication_date 2026/05/01 · openalex created_date 2026/05/03 · openalex updated_date 2026/07/02
Aims: To investigate the prevalence and histopathological spectrum of renal lesions in autopsy cases at a tertiary care center to identify subclinical and unsuspected renal diseases.Methods: A retrospective descriptive study of 420 autopsy cases was conducted between January and December 2023. Renal tissues were fixed in 10% neutral buffered formalin, embedded in paraffin, and stained with hematoxylin and eosin (H&E) for microscopic evaluation.Results: Definitive renal pathology was identified in 140 cases (33.33%). Tubulointerstitial lesions were the most frequent findings (45%), with acute kidney injury (AKI) accounting for 38.57% of pathological cases. Other incidental findings included simple cysts (7.85%), glomerulosclerosis (5%), renal infarction (1.42%), and metastatic carcinoma (0.71%).Conclusions: Autopsy remains a critical tool for identifying silent renal pathologies, such as subclinical AKI and incidental malignancies, which contribute to improved clinicopathological correlation and quality assurance.