Connectivity mapping with isotretinoin’s transcriptomic signature identifies alternative therapeutics for severe acne

2025/12/19 by Mackenzie L. Sennett, Robert P. Feehan, Tierney E. Wallace +7 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Acne and Rosacea Treatments and Effects #Retinoids in leukemia and cellular processes #melanin and skin pigmentation

paper · doi:10.1016/j.jid.2025.11.025

openalex created_date 2025/12/19 · openalex publication_date 2025/12/19 · crossref created 2025/12/19 · openalex updated_date 2026/06/26 · crossref deposited 2026/06/26 · crossref indexed 2026/06/26 · crossref issued 2026/07/01 · crossref published 2026/07/01 · crossref published-print 2026/07/01

Citations

• Complex heatmap visualization

Cited by

• Isotretinoin’s transcriptomics: Much more than mTORC1 inhibition

Discussions

• A report by Mackenzie Sennett et al., "Connectivity mapping with isotretinoin’s transcriptomic signature identifies alternative therapeutics for severe acne" https://doi.org/10.1016/j.jid.2025.11.025 [bsky, 0 points, 0 comments]