Extending support for mouse data in the Molecular Signatures Database (MSigDB)

2023/09/13 by Anthony S. Castanza, Jill M. Recla, David Eby +3 · 1 voice · 25 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Proteomics Techniques and Applications #Cancer, Hypoxia, and Metabolism #Metabolomics and Mass Spectrometry Studies

paper · doi:10.1038/s41592-023-02014-7

crossref issued 2023/09/13 · crossref published 2023/09/13 · crossref published-online 2023/09/13 · openalex publication_date 2023/09/13 · crossref created 2023/09/13 · crossref published-print 2023/11/01 · crossref deposited 2023/11/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30 · crossref indexed 2026/07/31

Cited by

• Single-cell and spatial transcriptomics implicate vascular cell orchestration of inflammatory changes after UV light exposure in skin
• Crosslinked ionizable lipids reprogram dendritic cell metabolism for potent mRNA vaccination
• Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells
• IL-17–producing γδ T cells in the tumor microenvironment promote radioresistance in mice
• Genome assembly and annotation of the olive grass mouse Abrothrix olivacea reveal transcriptomic and cellular adaptations across contrasting biomes
• Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation
• MOFA-FLEX: A Factor Model Framework for Integrating Omics Data with Prior Knowledge
• Early Neutrophil Sensing Shapes the Innate Response to Preneoplastic Mammary Cells
• Selective remodelling of the adipose niche in obesity and weight loss
• Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer
• The innate thermogenic capacity of brown adipose tissue develops independently of sympathetic signaling
• FOXA1 loss drives basal/squamous de-differentiation of prostate cancer and induces an immunosuppressive tumor microenvironment
• Deletion of 9p drives B-ALL through heterozygous inactivation of Pax5 and Cd72 in preleukemic cells
• Identification of medication–microbiome interactions that affect gut infection
• Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy
• Cellular signaling within aged skeletal muscle reveals a dysregulated stress‐induced remodeling response following volumetric muscle loss in female mice
• Body-wide multi-omic counteraction of aging with GLP-1R agonism
• Clinicogenomic Characterization of Primary Sclerosing Cholangitis–Associated Biliary Tract Cancers
• Control of Cellular Differentiation Trajectories for Cancer Reversion
• Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype
• Resource: A curated database of brain-related functional gene sets (Brain.GMT)
• Integrative transcriptomic identification of cellular senescence beyond marker limitations
• Predictive modeling of molecular activity underlying physical cell-cell interactions
• Obesogenic diet alters decidual differentiation and cell-cell communication in the mouse uterus
• Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression

Discussions

• 📓 New in Nature Methods from @natureportfolio.bsky.social, "Extending support for mouse data in the Molecular Signatures Database (MSigDB)" with Jill M Recla & Carol Bult: #jaxresearch doi.org/10.1 [bsky, 1 points, 0 comments]