Cell–matrix and cell–cell interaction mechanics in guiding migration

2023/08/23 by Hoang Anh Le, Roberto Mayor · 1 voice
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #3D Printing in Biomedical Research #Cancer Cells and Metastasis #Cellular Mechanics and Interactions

paper · pdf · doi:10.1042/bst20230211

openalex publication_date 2023/08/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

Physical properties of tissue are increasingly recognised as major regulatory cues affecting cell behaviours, particularly cell migration. While these properties of the extracellular matrix have been extensively discussed, the contribution from the cellular components that make up the tissue are still poorly appreciated. In this mini-review, we will discuss two major physical components: stiffness and topology with a stronger focus on cell-cell interactions and how these can impact cell migration.

Citations

• Mechanical regulation of glycolysis via cytoskeleton architecture

Discussions

• 4/4: Now I have moved into the field of immuno-mechanobiology. I love it so much because I get to study my favorite cell type of all time: macrophages, and watch them move every day. Here is a review [bsky, 1 points, 0 comments]

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