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p -Cymene–Ru( ii )–organometallic conjugates based on ‘V-shaped’ 4-amino-1,8-naphthalimide Tröger's base scaffolds: synthesis, photophysics, bioimaging, and BSA/HSA binding studies

2025/01/01 by Binduja Mohan, Anna Jose, Indrajit Bhattacharjee +5 · 1 voice
Chemistry · Computer Science · Medicine · #Computational Drug Discovery Methods #Metal complexes synthesis and properties #Molecular spectroscopy and chirality

paper · pdf · doi:10.1039/d5dt00769k

openalex publication_date 2025/01/01 · openalex created_date 2025/06/12 · openalex updated_date 2026/08/01

Abstract

. Additionally, cellular uptake studies using the 3T3 (embryonic mouse fibroblast) cell line demonstrated rapid internalisation with minimal cytotoxicity, suggesting the potential of these conjugates as bioimaging probes. These results underscore the possible applications of newly designed TBNap-based Ru(II) organometallic conjugates in biomedical fields.

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