Behind the folding funnel diagram

2011/06/17 by Martin Karplus · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Enzyme Structure and Function #Protein Structure and Dynamics #RNA and protein synthesis mechanisms

paper · doi:10.1038/nchembio.565

crossref issued 2011/06/17 · crossref published 2011/06/17 · crossref published-online 2011/06/17 · openalex publication_date 2011/06/17 · crossref created 2011/06/17 · crossref published-print 2011/07/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · crossref indexed 2026/06/17 · openalex updated_date 2026/07/29

Cited by

• AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
• Atomistic molecular simulations of protein folding

Discussions

• While the formulations are very different, related issues are described well in a paper from Karplus about the folding funnel (and why most people mis-interpret the image of a funnel). Behind the fol [bsky, 1 points, 1 comments]