Cell instructive hydrogels functionalized with polymerized DNA nanostructures

2025/12/02 by Hee Yeon Kim, Young‐Min Kim, Keonwook Nam +4 · 1 voice
Biochemistry, Genetics and Molecular Biology · Engineering · #3D Printing in Biomedical Research #Advanced Materials and Mechanics #Hydrogels: synthesis, properties, applications

paper · doi:10.1039/d5nh00521c

openalex created_date 2025/12/02 · openalex publication_date 2025/12/02 · openalex updated_date 2026/05/21

Abstract

Novel hyaluronic acid hydrogels functionalized with polymerized DNA nanostructures using rolling circle amplification were developed. These hydrogels exhibited enhanced cell attachment and proliferation through functional DNA-mediated interactions. The system maintained favorable physicochemical properties and enhanced interactions with biological interfaces, demonstrating potential for advanced 3D cell culture applications.

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• Nanoscale Horizons issue 2 is out now! Featuring this cover article by Young Hoon Roh et al. on 'Cell instructive hydrogels functionalized with polymerized DNA nanostructures' Read the full article h [bsky, 1 points, 0 comments]

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