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Molecular insights into the role of selenoenzymes in the toxicity of methylmercury

2025/11/25 by Mikel Bernabeu de Maria, Tshering Zangmo, Andrzej Gawor +6 · 1 voice
Environmental Science · Nursing · Pharmacology, Toxicology and Pharmaceutics · #Mercury impact and mitigation studies #Selenium in Biological Systems #Organoselenium and organotellurium chemistry

paper · doi:10.1039/d5qi01958c

openalex publication_date 2025/11/25 · openalex created_date 2025/11/25 · openalex updated_date 2026/07/22

Abstract

This combined experimental and computational approach provides a comprehensive mechanistic understanding of how selenoproteins modulate methylmercury toxicity through its preferential reactivity towards SeCys,leading to S–Hg–S(e) bridge formation.

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