2026/07/06 by Coline Wiame, Hadi Loutfi, Kirill Sheberstov +1 · 1 voice
Chemistry · Medicine · Physics and Astronomy · #Advanced MRI Techniques and Applications #Advanced NMR Techniques and Applications #NMR spectroscopy and applications
paper · pdf · doi:10.5194/mr-2026-9
openalex publication_date 2026/07/06 · openalex created_date 2026/07/07 · openalex updated_date 2026/07/27
Abstract. Selective Spin-Locking (SSL) of the magnetisation vectors of selected singlets or multiplets in high-resolution Nuclear Magnetic Resonance (NMR) spectra by mono- or polychromatic selective radio-frequency (RF) irradiation can reduce the line-widths to the limit given by homogeneous T1ρ relaxation. The resulting line-narrowing leads to an increase in signal height of spectra of 1H, 19F, 31P or other nuclei that is in principle only limited by the ratio T1ρ/T2*. At the same time, the scalar interactions that give rise to multiplets are decoupled, thus leading to an additional gain in signal height. Common one-dimensional (1D) experiments such as inversion recovery (IR) as well as the excitation and reconversion of Long-Lived States (LLS) by Spin-Lock Induced Crossing (SLIC) can significantly benefit from SSL.