2021/03/01 by Stephen J. DeVience, DeVience, Stephen J., Mason Greer +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Physics and Astronomy · #Advanced NMR Techniques and Applications #Chemical Physics (physics.chem-ph) #Electron Spin Resonance Studies #FOS: Physical sciences #NMR spectroscopy and applications #Other Condensed Matter (cond-mat.other) #Quantum Physics (quant-ph)
paper · pdf · doi:10.48550/arxiv.2103.01289
openalex publication_date 2021/03/01 · openalex created_date 2022/07/25 · openalex updated_date 2026/07/28
Nuclear magnetic resonance (NMR) spectroscopy usually requires high magnetic\nfields to create spectral resolution among different proton species. At low\nfields, chemical shift dispersion is insufficient to separate the species, and\nthe spectrum exhibits just a single line. In this work, we demonstrate that\nspectra can nevertheless be acquired at low field using a novel pulse sequence\ncalled spin-lock induced crossing (SLIC). This probes energy level crossings\ninduced by a weak spin-locking pulse and produces a unique J-coupling spectrum\nfor most organic molecules. Unlike other forms of low-field J-coupling\nspectroscopy, our technique does not require the presence of heteronuclei and\ncan be used for most compounds in their native state. We performed SLIC\nspectroscopy on a number of small molecules at 276 kHz and 20.8 MHZ, and we\nshow that SLIC spectra can be simulated in good agreement with measurements.\n