Anionic 5- endo-dig cyclizations: an experimental investigation of in-plane aromaticity involving a non-enolate carbanion nucleophile

2025/01/01 by Kristina M. Nugent, Silas Q. Hintze, Pradip Maity +1 · 1 voice
Chemistry · #Catalytic Alkyne Reactions #Cyclopropane Reaction Mechanisms #Asymmetric Synthesis and Catalysis

paper · pdf · doi:10.1039/d5qo00547g

openalex publication_date 2025/01/01 · openalex created_date 2025/08/02 · openalex updated_date 2026/06/24

Abstract

an early ambimodal transition state. Experimental results are presented with a view to refining existing mechanistic models for this growing class of alkyne reactions.

Discussions

• Anionic 5-𝘦𝘯𝘥𝘰-𝘥𝘪𝘨 cyclizations: an experimental investigation of in-plane aromaticity involving a non-enolate carbanion nucleophile ✨ New insights into alkyne cyclizations under mild, metal-f [bsky, 2 points, 0 comments]

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