The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature – a critical evaluation of Akiyoshi, 2025

2026/02/01 by Maximilian W. D. Raas, Jolien J. E. Van Hooff, J. Lukes +6 · 2 voices · 1 citation
Biochemistry, Genetics and Molecular Biology · #Cellular transport and secretion #Microtubule and mitosis dynamics #Protist diversity and phylogeny

paper · pdf · doi:10.1242/jcs.264452

openalex publication_date 2026/02/01 · openalex created_date 2026/02/14 · openalex updated_date 2026/07/26

Abstract

Summary: Akiyoshi, 2025 presented a hypothesis with implications for the early evolution of eukaryotes and eukaryotic cell division machinery. In this Correspondence, the authors conclude that this hypothesis leads to a highly implausible scenario.

Citations

• Reconstructing the last common ancestor of all eukaryotes
• A robustly rooted tree of eukaryotes reveals their excavate ancestry
• Hypothesis that ancestral eukaryotes sexually proliferated without kinetochores or mitosis

Cited by

• Euglenozoa are paraphyletic if the eukaryotic root lies between glycomonads and the rest of eukaryotes. Response to ‘The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature’

Discussions

• The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature – a critical evaluation of Akiyoshi, 2025 #eukaryotes #evolution doi.org/10.1242/jcs.... [bsky, 2 points, 1 comments]
• The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature – a critical evaluation of Akiyoshi, 2025 doi.org/10.1242/jcs.... [bsky, 0 points, 1 comments]

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