Prodrug-tethered lipid nanoparticles for synergistic messenger RNA cancer immunotherapy

2026/03/01 by Qiangqiang Shi, Ningqiang Gong, Jinjin Wang +25 · 1 voice
Engineering · Medicine · Neuroscience · #Cancer Immunotherapy and Biomarkers #Nanoplatforms for cancer theranostics #Tryptophan and brain disorders

paper · doi:10.1038/s41565-025-02102-z

crossref issued 2026/03/01 · crossref published 2026/03/01 · crossref published-print 2026/03/01 · openalex publication_date 2026/03/01 · crossref published-online 2026/03/18 · crossref created 2026/03/18 · openalex created_date 2026/03/20 · crossref deposited 2026/03/25 · crossref indexed 2026/06/16 · openalex updated_date 2026/07/27

Citations

• Roles of IFN-γ in tumor progression and regression: a review
• Systemic immunity in cancer
• Interleukins in cancer: from biology to therapy
• Lipid nanoparticles for mRNA delivery
• mRNA vaccines for infectious diseases: principles, delivery and clinical translation

Discussions

• 1. A new @natnano.nature.com paper from senior author Dr. Michael J Mitchell and his team that described pLNPs designed to enhance messenger RNA cancer immunotherapy by co-delivering interleukin-12 an [bsky, 2 points, 1 comments]