Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

2020/04/22 by You-Hyang Song, Yang-Sun Hwang, Kwansoo Kim +10 · 1 voice · 1 citation
Neuroscience · #Neural dynamics and brain function #Photoreceptor and optogenetics research #Neuroscience and Neuropharmacology Research

paper · pdf · doi:10.1126/sciadv.aaz0517

openalex publication_date 2020/04/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

Somatostatin improves visual perception by reducing excitatory inputs to the parvalbumin-positive interneurons in the cortex.

Cited by

• Somatostatin-expressing interneurons induce early NO-driven and late specific astrocyte-mediated vasodilation

Discussions

• ⬆️Great points @kenmiller.bsky.social in addition to vascular coupling, inhibitory neurons are highly active + metabolically specialized, so they might be uniquely vulnerable. loss of somatostatin it [bsky, 3 points, 0 comments]

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