New Opportunities to Access Fluorinated Molecules Using Organophotoredox Catalysis via C(sp³)–F Bond Cleavage

2025/02/07 by Sourav Roy, Tatiana Besset · 1 voice · 1 citation
Pharmacology, Toxicology and Pharmaceutics · Chemistry · #Fluorine in Organic Chemistry #Radical Photochemical Reactions #Catalytic C–H Functionalization Methods

paper · doi:10.1021/jacsau.4c01158

openalex publication_date 2025/02/07 · openalex created_date 2025/02/08 · openalex updated_date 2026/07/28

Abstract

)-F bond activation or β-fragmentation. This Perspective will highlight remaining challenges and discuss future research opportunities.

Citations

• Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
• Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds
• Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis
• Contemporary synthetic strategies in organofluorine chemistry

Cited by

• Selective defluorinative [4 + 3] annulation to access fluorinated oxazepines and thiazepines

Discussions

• Take a look at this great perspective now published in #JACSAu in @acs.org from the groups of Besset & Roy doi.org/10.1021/jacs... @cnrs.bsky.social [bsky, 3 points, 0 comments]

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