Burn the Fat: Colon Cancer Tumors Are Skilled at Lipid Storage During Obesity

2024/10/23 by Arianne L. Theiss, Christopher Williams, Christopher S. Williams · 1 voice
Biochemistry, Genetics and Molecular Biology · #Cancer, Lipids, and Metabolism

paper · pdf · doi:10.1053/j.gastro.2024.10.021

openalex publication_date 2024/10/23 · crossref created 2024/10/23 · crossref issued 2025/02/01 · crossref published 2025/02/01 · crossref published-print 2025/02/01 · openalex created_date 2025/10/10 · crossref deposited 2026/05/13 · crossref indexed 2026/05/13 · openalex updated_date 2026/07/30

Citations

• Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society
• Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Discussions

• 🔥 Colon cancer cells hijack fat metabolism! Ghimire et al. show obesity boosts DGAT1/2, fueling tumor growth via lipid storage & MYC signaling. Blocking these enzymes halts cancer progression in mice [bsky, 3 points, 0 comments]