Genotype and injury severity modulate the effects of traumatic brain injury on sleep in Drosophila

2026/01/22 by Leah Pisano, Michael P. Shahandeh · 1 voice
Medicine · Neuroscience · #Traumatic Brain Injury Research #Sleep and Wakefulness Research #Traumatic Brain Injury and Neurovascular Disturbances

paper · doi:10.17912/micropub.biology.002034

openalex publication_date 2026/01/22 · openalex created_date 2026/03/17 · openalex updated_date 2026/07/01

Abstract

from two genetic backgrounds to two TBI severity treatments and measured effects on sleep. We document significantly increasing effects with injury severity in both genetic backgrounds and describe differences between genotypes, demonstrating a genetic basis to susceptibility.

Discussions

• Congrats to Lynbrook HS senior Leah Pisano, who just published her Regeneron Science Talent Search project in microPublication Biology! This was a departure for my lab, which speaks to Leah's independ [bsky, 3 points, 0 comments]

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