The mesoSPIM initiative: open-source light-sheet mesoscopes for imaging in cleared tissue

2019/03/18 by Fabian F. Voigt, Daniel S. Kirschenbaum, Evgenia Platonova +27 · 1 voice
Biochemistry, Genetics and Molecular Biology · Engineering · #Advanced Electron Microscopy Techniques and Applications #Advanced Fluorescence Microscopy Techniques #Near-Field Optical Microscopy

paper · pdf · doi:10.1101/577122

openalex publication_date 2019/03/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

Over the course of the past decade, tissue clearing methods have reached a high level of sophistication with a wide variety of approaches now available[1][1]. To image large cleared samples, light-sheet microscopes have proven to be ideal due to their excellent optical sectioning capability in

Citations

• Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy

Discussions

• The #mesoSPIM initiative: #OpenSource light-sheet #mesoscopes for #imaging in cleared #tissue: Preprint article: doi.org/10.1101/577122 GitHub: github.com/mesoSPIM #DIYbio #lab #instruments #microsc [bsky, 4 points, 0 comments]

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