2020/01/01 by Qiuxiang Wang, Yue Sun, Shangfei Li +2 · 1 citation
Chemistry · Engineering · Medicine · #Boron Compounds in Chemistry #Metal-Organic Frameworks: Synthesis and Applications #Nanoplatforms for cancer theranostics
paper · pdf · doi:10.1039/d0ra07950b
openalex publication_date 2020/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30
has been extensively studied in the medical field due to its low toxicity and good biocompatibility. This review introduces the preparation and functional modification of ZIF-8, and its application in drug delivery, focusing on the single-stimulus and multi-stimulus response release of drugs in ZIF-8 materials, the integrated role of diagnosis and treatment with ZIF-8 in cancer treatment, and its application in the synergistic therapy of multiple cancer treatment methods. We summarize the latest developments of ZIF-8 in the field of drug delivery and tumor therapy, and present the main challenges that remain to be resolved in the ZIF-8 drug delivery system.