Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

2021/01/28 by Simon Alberti, Anthony A. Hyman · 35 citations
Biochemistry, Genetics and Molecular Biology · #Nuclear Structure and Function #RNA Research and Splicing #RNA modifications and cancer

paper · doi:10.1038/s41580-020-00326-6

crossref issued 2021/01/28 · crossref published 2021/01/28 · crossref published-online 2021/01/28 · openalex publication_date 2021/01/28 · crossref created 2021/01/28 · crossref published-print 2021/03/01 · crossref deposited 2023/05/20 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31

Citations

• The Biology of Proteostasis in Aging and Disease
• Protein Misfolding, Functional Amyloid, and Human Disease
• ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
• Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
• Liquid–Liquid Phase Separation in Disease
• Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences
• Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
• G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

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