Drug delivery systems for RNA therapeutics

2022/01/04 by Kalina Paunovska, David Loughrey, James E. Dahlman · 12 citations
Biochemistry, Genetics and Molecular Biology · #Advanced biosensing and bioanalysis techniques #RNA Interference and Gene Delivery #Virus-based gene therapy research

paper · pdf · doi:10.1038/s41576-021-00439-4

crossref issued 2022/01/04 · crossref published 2022/01/04 · crossref published-online 2022/01/04 · openalex publication_date 2022/01/04 · crossref created 2022/01/04 · crossref published-print 2022/05/01 · crossref deposited 2024/12/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30 · crossref indexed 2026/07/30

Citations

• A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery
• Silencing disease genes in the laboratory and the clinic
• Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
• An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
• Advances in oligonucleotide drug delivery
• Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
• Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
• The evolution of commercial drug delivery technologies
• Extracellular vesicles as a next-generation drug delivery platform
• CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
• Lipids and Lipid Derivatives for RNA Delivery

Cited by

• Plant-derived nanovesicles and therapeutic application
• TAV2b Peptide Derivatives Underwind and Stabilize Double-Stranded RNA upon Binding
• Structure and biochemistry-guided engineering of an all-RNA system for DNA insertion with R2 retrotransposons
• Context-dependent translation inhibition as a novel oncology therapeutic modality
• Opportunities for RNA sequencing in physiology: from big data to understanding homeostasis and heterogeneity
• In vivo CAR engineering for immunotherapy
• Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning
• <i>In Vivo</i> Prime Editing by Lipid Nanoparticle Co-Delivery of Chemically Modified pegRNA and Prime Editor mRNA
• Therapeutic in vivo delivery of gene editing agents
• Environment‐Responsive Peptide Dimers Bind and Stabilize Double‐Stranded RNA
• A material toolbox for engineering targeted lipid nanoparticles for RNA therapies
• The evolving landscape of gene therapy strategies for the treatment of osteoarthritis