First report of autochthonous transmission of Zika virus in Brazil

2015/06/04 by Camila Zanluca, Vanessa Campos Andrade de Melo, Ana Luiza Pamplona Mosimann +4 · 16 citations
Medicine · #Malaria Research and Control #Mosquito-borne diseases and control #Viral Infections and Vectors

paper · pdf · doi:10.1590/0074-02760150192

openalex publication_date 2015/06/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.

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