2008/05/07 by Rachel Gordon, Rachel J. Gordon, Franklin D. Lowy +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Antimicrobial Resistance in Staphylococcus #Bacterial Identification and Susceptibility Testing #Bacterial biofilms and quorum sensing
paper · pdf · doi:10.1086/533591
openalex publication_date 2008/05/07 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/01
Staphylococcus aureus is a versatile pathogen capable of causing a wide range of human diseases. However, the role of different virulence factors in the development of staphylococcal infections remains incompletely understood. Some clonal types are well equipped to cause disease across the globe, whereas others are facile at causing disease among community members. In this review, general aspects of staphylococcal pathogenesis are addressed, with emphasis on methicillin-resistant strains. Although methicillin-resistant S. aureus (MRSA) strains are not necessarily more virulent than methicillin-sensitive S. aureus strains, some MRSA strains contain factors or genetic backgrounds that may enhance their virulence or may enable them to cause particular clinical syndromes. We examine these pathogenic factors.