2012/09/07 by Jean‐Marc Nicaud · 5 citations
Biochemistry, Genetics and Molecular Biology · #Microbial Metabolic Engineering and Bioproduction #RNA and protein synthesis mechanisms #Enzyme Catalysis and Immobilization
paper · pdf · doi:10.1002/yea.2921
The yeast Yarrowia lipolytica presents specific physiological, metabolic and genomic characteristics, which differentiate it from the model yeast Saccharomyces cerevisiae. These properties have led several research groups to use this yeast as a model for basic knowledge. Thanks to the development of advanced genetic tools and -omic approaches, significant progress has been achieved in the understanding of specific biological processes. This review, after a short presentation of this model yeast, will briefly highlight the different use of Y. lipolytica for basic knowledge and the advantages gained by exploiting this non-conventional yeast. Future perspectives in employing this yeast for basic knowledge in the field of RNA splicing and genome evolution, and for the study of lipid metabolism, are also discussed.