2022/06/18 by Amrit Gopan, Moinak Sen Sarma, Bappaditya Har +5
Medicine · #Neuroendocrine Tumor Research Advances #Pancreatic and Hepatic Oncology Research #Pediatric Hepatobiliary Diseases and Treatments
paper · doi:10.1111/jpc.16060
openalex publication_date 2022/06/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The extrahepatic biliary apparatus is a rare site for neuroendocrine tumours. A 13-year-old child presented with cholestatic symptoms of jaundice and pruritus with soft hepatomegaly and mild ascites. Magnetic resonance imaging and endoscopic ultrasound revealed a mid-common bile duct mass, and dilated intrahepatic biliary system. An en-bloc resection of the extrahepatic biliary apparatus, showed malignant cells disposed in lobules in a desmoplastic stroma with intramural invasion, staining positive for cytokeratin, chromogranin, synaptophysin and negative for CD56. At 3 months post-resection, whole body positron emission tomography scan was normal with no recurrence at 24 months.