Cancer during HIV infection

2020/01/28 by Marinho Marques da Silva Neto, Carlos Brites, Álvaro H. Borges
Medicine · #HIV/AIDS Research and Interventions #Polyomavirus and related diseases #Viral-associated cancers and disorders

paper · pdf · doi:10.1111/apm.13020

openalex publication_date 2020/01/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25

Abstract

HIV+ persons have a significantly increased risk of cancer when compared to the general population. The excess cancer risk observed during HIV infection is particularly higher for infection-related malignancies. Mechanisms underlying this remain unclear, but both HIV-related and HIV-unrelated factors have been postulated to play a role. Here, we (i) review newly published data on cancer burden in the setting of HIV infection with a focus on HIV-related risk factors for cancer; (ii) discuss emerging data on cancer among HIV+ persons living in low- and middle-income countries; and (iii) review guideline recommendations for cancer screening among HIV+ persons and discuss ongoing studies investigating strategies for cancer screening among HIV+ patients.

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