2006/05/01 by Takumi Nishiuchi, Daisuke Masuda, Hideo Nakashita +7
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Mycotoxins in Agriculture and Food #Plant Pathogens and Fungal Diseases #Plant-Microbe Interactions and Immunity
paper · doi:10.1094/mpmi-19-0512
openalex publication_date 2006/05/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/29
Phytopathogenic fungi such as Fusarium spp. synthesize trichothecene family phytotoxins. Although the type B trichothecene, deoxynivalenol (DON), is thought to be a virulence factor allowing infection of plants by their trichothecene-producing Fusarium spp., little is known about effects of trichothecenes on the defense response in host plants. Therefore, in this article, we investigated these effects of various trichothecenes in Fusarium-susceptible Arabidopsis thaliana. Necrotic lesions were observed in Arabidopsis leaves infiltrated by 1 microM type A trichothecenes such as T-2 toxin. Trichothecene-induced lesions exhibited dead cells, callose deposition, generation of hydrogen peroxide, and accumulation of salicylic acids. Moreover, infiltration by trichothecenes caused rapid and prolonged activation of two mitogen-activated protein kinases and induced expression of both PR-1 and PDF1.2 genes. Thus, type A trichothecenes trigger the cell death by activation of an elicitor-like signaling pathway in Arabidopsis. Although DON did not have such an activity even at 10 microM, translational inhibition by DON was observed at concentrations above 5 microM. These results suggested that DON is capable of inhibiting translation in Arabidopsis cells without induction of the elicitor-like signaling pathway.