The clinical spectrum of aspergillosis in chronic obstructive pulmonary disease

2023/01/20 by Akaninyene Otu, Chris Kosmidis, Alexander G. Mathioudakis +2 · 1 citation
Medicine · #Antifungal resistance and susceptibility #Fungal Infections and Studies #Respiratory and Cough-Related Research

paper · pdf · doi:10.1007/s15010-022-01960-2

openalex publication_date 2023/01/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. In this review, we present the clinical spectrum and pathogenesis of syndromes caused by Aspergillus in COPD namely invasive aspergillosis (IA), community-acquired Aspergillus pneumonia, chronic pulmonary Aspergillosis and Aspergillus sensitisation. Some of these entities are clearly linked to COPD, while others may coexist, but are less clearly liked directly to COPD. We discuss current uncertainties as these pertain to IA in COPD cohorts and explore areas for future research in this field.

Citations

• Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019

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