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FAPI PET/CT Immune-Fibrosis Imaging for New Insights into Rheumatologic Disorders

2023/09/21 by Christian Schmidkonz, Armin Atzinger, Andreas Ramming +1
Medicine · Biochemistry, Genetics and Molecular Biology · #Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis #Peptidase Inhibition and Analysis #Protease and Inhibitor Mechanisms

paper · pdf · doi:10.2967/jnumed.123.266182

Abstract

Immune-mediated diseases are associated with substantial activation of tissue-resident fibroblasts resulting in fibrosis and organ damage ([1][1]). Despite the overall low incidence of fibrotic diseases, fibrotic tissue responses across different diseases have been estimated to account for up to 45

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