2025/01/01 by Göen, Thomas, Müller, Johannes, Hoppe, Hans-Wolfgang +2
Biochemistry, Genetics and Molecular Biology · Environmental Science · Medicine · #(Propan-2-yl)benzen #(Propan-2-yl)benzol #1 #1-Phenylpropan #1-Phenylpropane #1‐Propylbenzen #1‐Propylbenzene #1‐Propylbenzol #2 #2-Dimethylbenzen #2-Dimethylbenzene #2-Dimethylbenzol #3 #3-Dimethylbenzen #3-Dimethylbenzene #3-Dimethylbenzol #3-Trimethylbenzen #3-Trimethylbenzene #3-Trimethylbenzol #4-Dimethylbenzen #4-Dimethylbenzene #4-Dimethylbenzol #4-Trimethylbenzen #4-Trimethylbenzene #4-Trimethylbenzol #5-Trimethylbenzen #5-Trimethylbenzene #5-Trimethylbenzol #543 Analytical chemistry #543 Analytische Chemie #571.95 Toxicology #571.95 Toxikologie #5‐Tetramethylbenzen #5‐Tetramethylbenzene #5‐Tetramethylbenzol #616.9803 Betriebs- und Arbeitsmedizin #616.9803 Industrial and occupational medicine #Allgemeinbevölkerung #Analysen in biologischem Material #Analysenmethode #Analyses in Biological Materials #Arbeiter #Arbeitnehmer #Arbeitsplatz #Arbeitsplatzbelastung #Aromaten #BTX hydrocarbons #BTX-Aromaten #Benzen #Benzene #Benzol #Biomedical and Chemical Research #Biomonitoring #Biomonitoringmethode #Blut #Carcinogens and Genotoxicity Assessment #Chlorbenzen #Chlorbenzol #Chlorobenzene #Cumen #Cumene #Cumol #Dampfraum #Dimethylbenzen (alle Isomere) #Dimethylbenzene (all isomers) #Dimethylbenzol (alle Isomere) #Ethenylbenzen #Ethenylbenzene #Ethenylbenzol #Ethylbenzen #Ethylbenzene #Ethylbenzol #HBM #HS-GC #HS-GC-MS #Headspace-GC-MS #Headspace-Gaschromatographie mit Massenspektrometrie #Hemimelliten #Hemimellitene #Hemimellitol #Hintergrundbelastung #Humanbiomonitoring #Indoor Air Quality and Microbial Exposure #Intoxikation #Isocumen #Isocumene #Isocumol #Isoduren #Isodurene #Isodurol #Isopropylbenzen #Isopropylbenzene #Isopropylbenzol #Mesitylen #Mesitylene #Methode #Methylbenzen #Methylbenzene #Methylbenzol #Monochlorbenzen #Monochlorbenzol #Monochlorobenzene #Phenylethen #Phenylethene #Pseudocumen #Pseudocumene #Pseudocumol #Styren #Styrene #Styrol #Toluen #Toluene #Toluol #Trimethylbenzen (alle Isomere) #Trimethylbenzene (all isomers) #Trimethylbenzol (alle Isomere) #Umweltbelastung #Vergiftung #Vinylbenzen #Vinylbenzene #Vinylbenzol #Xylen (alle Isomere) #Xylene (all isomers) #Xylol (alle Isomere) #analytical method #aromatic compounds #aromatics #aromatische Verbindungen #background exposure #biological monitoring #biologisches Monitoring #biomonitoring #biomonitoring method #blood #employee #environmental exposure #general population #headspace gas chromatography #headspace-GC-MS #headspace-gas chromatography with mass spectrometry #human biomonitoring #intoxication #m-Xylen #m-Xylene #m-Xylol #method #n-Propylbenzen #n-Propylbenzol #n‐Propylbenzene #o-Xylen #o-Xylene #o-Xylol #p-Xylen #p-Xylene #p-Xylol #poisoning #worker #workplace #workplace exposure
paper · doi:10.34865/bi7143e2218_w
openalex publication_date 2025/01/01 · openalex created_date 2025/12/13 · openalex updated_date 2026/07/01
The working group „Analyses in Biological Materials“ of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area verified the presented biomonitoring method. The here described analytical method enables the simultaneous determination of benzene, toluene, chlorobenzene, ethylbenzene, o‐xylene, m‐xylene, p‐xylene, styrene, n‐propylbenzene, isopropylbenzene (cumene), 1,2,3‐trimethylbenzene (hemimellitene), 1,2,4‐trimethylbenzene, 1,3,5‐trimethylbenzene (mesitylene) and 1,2,3,5‐tetramethylbenzene (isodurene) in blood. For determination, the blood samples are introduced into headspace vials. The vials are sealed and heated to 50 °C in the autosampler. Subsequently, an aliquot of the vapour phase is injected into the GC-system and analysed using mass spectrometry. Calibration standards are prepared in ovine blood and processed in the same way as the samples to be analysed.