2025/04/30 by Hartwig, Andrea, MAK Commission
#(E)-1 #3 #3-Tetrafluoroprop-1-ene #3-Tetrafluoropropene #3-Tetrafluoropropylene #3-Tetrafluorprop-1-en #3-Tetrafluorpropen #3-Tetrafluorpropylen #571.95 Toxicology #571.95 Toxikologie #616.9803 Betriebs- und Arbeitsmedizin #616.9803 Industrial and occupational medicine #Blut:Luft-Verteilungskoeffizient #Luft #MAK value #MAK-Wert #air #blood:air distribution coefficient #maximale Arbeitsplatzkonzentration #maximum workplace concentration #trans-1
paper · doi:10.34865/mb2911824e6619_w
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the workplace (MAK value) of trans‐1,3,3,3‐tetrafluoropropene [29118‐24‐9]. As the blood:air partition coefficient of trans‐1,3,3,3‐tetrafluoropropene is < 5, the increased respiratory volume at the workplace (see List of MAK and BAT Values, Sections I b and I c) does not have to be taken into account for the derivation of the MAK value. Even after extrapolation of 6‐hour exposure in the animal experiment to 8‐hour exposure at the workplace, the MAK value for trans‐1,3,3,3‐tetrafluoropropene of 1000 ml/m3 can be retained.