Upregulation of RAGE and its ligands in proliferative retinal disease

2006/02/04 by Sophia I. Pachydaki, Samir Tari, Samir R. Tari +12 · 19 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Glycation End Products research #Biology #Diabetes mellitus #Diabetic retinopathy #Endocrinology #Epiretinal membrane #Glaucoma and retinal disorders #Immunohistochemistry #Medicine #Ophthalmology #Pars plana #Pathology #Proliferative vitreoretinopathy #Rage (emotion) #Retinal #Retinal Diseases and Treatments #Retinal detachment #Vimentin #Visual acuity #Vitrectomy #Vitreous hemorrhage

paper · doi:10.1016/j.exer.2005.09.022

openalex publication_date 2006/02/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Cited by

• AGEs Promote Oxidative Stress and Induce Apoptosis in Retinal Pigmented Epithelium Cells RAGE-dependently
• Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials. [europepmc]
• Diabetes: impaired damage control. [europepmc]
• Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. [europepmc]
• Molecular Markers of Diabetic Retinopathy: Potential Screening Tool of the Future? [europepmc]
• The Role of HMGB1 in the Pathogenesis of Type 2 Diabetes. [europepmc]
• Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls. [europepmc]
• Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects. [europepmc]
• Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and mTOR as a Therapeutic Target. [europepmc]
• BDNF Alleviates Neuroinflammation in the Hippocampus of Type 1 Diabetic Mice via Blocking the Aberrant HMGB1/RAGE/NF-κB Pathway. [europepmc]
• Role of HMGB1 signaling in the inflammatory process in diabetic retinopathy. [europepmc]
• Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders. [europepmc]
• Pathophysiology of RAGE in inflammatory diseases. [europepmc]
• Comparison of treatment outcomes of 360° intraoperative laser retinopexy and focal laser retinopexy with pars plans vitrectomy in patients with primary rhegmatogenous retinal detachment. [europepmc]
• RAGE plays key role in diabetic retinopathy: a review. [europepmc]
• Vitreous Olink proteomics reveals inflammatory biomarkers for diagnosis and prognosis of traumatic proliferative vitreoretinopathy. [europepmc]
• Targeting pericyte retention in Diabetic Retinopathy: a review. [europepmc]
• The role of high mobility group box-1 on the development of diabetes complications: A plausible pharmacological target. [europepmc]
• The AGE-RAGE-oxidative stress axis: A paradigm shift in understanding diabetic retinopathy. [europepmc]