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A Diffusion-Driven Temporal Super-Resolution and Spatial Consistency Enhancement Framework for 4D MRI imaging

2025/06/04 by Xuanru Zhou, Zhou, Xuanru, Jiarun Liu +11 · 1 citation
Computer Science · #Advanced Image Processing Techniques #Artificial Intelligence (cs.AI) #Computer Vision and Pattern Recognition (cs.CV) #Domain Adaptation and Few-Shot Learning #FOS: Computer and information sciences #FOS: Electrical engineering #Generative Adversarial Networks and Image Synthesis #Image and Video Processing (eess.IV) #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2506.04116

openalex publication_date 2025/06/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

In medical imaging, 4D MRI enables dynamic 3D visualization, yet the trade-off between spatial and temporal resolution requires prolonged scan time that can compromise temporal fidelity--especially during rapid, large-amplitude motion. Traditional approaches typically rely on registration-based interpolation to generate intermediate frames. However, these methods struggle with large deformations, resulting in misregistration, artifacts, and diminished spatial consistency. To address these challenges, we propose TSSC-Net, a novel framework that generates intermediate frames while preserving spatial consistency. To improve temporal fidelity under fast motion, our diffusion-based temporal super-resolution network generates intermediate frames using the start and end frames as key references, achieving 6x temporal super-resolution in a single inference step. Additionally, we introduce a novel tri-directional Mamba-based module that leverages long-range contextual information to effectively resolve spatial inconsistencies arising from cross-slice misalignment, thereby enhancing volumetric coherence and correcting cross-slice errors. Extensive experiments were performed on the public ACDC cardiac MRI dataset and a real-world dynamic 4D knee joint dataset. The results demonstrate that TSSC-Net can generate high-resolution dynamic MRI from fast-motion data while preserving structural fidelity and spatial consistency.

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