2007/10/04 by Philip Nelson, Philip C Nelson, Nelson, Philip C
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biomolecules (q-bio.BM) #DNA and Nucleic Acid Chemistry #Diffusion and Search Dynamics #Electrostatics and Colloid Interactions #FOS: Biological sciences #Quantitative Methods (q-bio.QM) #q-bio.BM #q-bio.QM
paper · pdf · doi:10.48550/arxiv.0710.1048
19pp. Accepted for publication in Curr Op Colloid Interf Science
arxiv created 2007/10/04 · openalex publication_date 2007/10/04 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Tethered particle motion is an experimental technique to monitor conformational changes in single molecules of DNA in real time, by observing the position fluctuations of a micrometer-size particle attached to the DNA. This article reviews some recent work on theoretical problems inherent in the interpretation of TPM experiments, both in equilibrium and dynamical aspects.