The blastema and epimorphic regeneration in mammals

2017/12/25 by Ashley W. Seifert, Ken Muneoka · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Engineering · #Developmental Biology and Gene Regulation #Reconstructive Surgery and Microvascular Techniques #Bone Tissue Engineering Materials

paper · doi:10.1016/j.ydbio.2017.08.007

Citations

• BMP2 induces segment-specific skeletal regeneration from digit and limb amputations by establishing a new endochondral ossification center
• SDF-1α/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2
• Development and regeneration of the neonatal digit tip in mice
• Wound healing and blastema formation in regenerating digit tips of adult mice

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• Differential fates of Kazald gene quartet: Ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds
• Proving Theorems with Athena
• Insights into regeneration tool box: An animal model approach. [europepmc]
• Regulation of Genomic Output and (Pluri)potency in Regeneration. [europepmc]
• Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence. [europepmc]
• Can laboratory model systems instruct human limb regeneration? [europepmc]
• Parallels between wound healing, epimorphic regeneration and solid tumors. [europepmc]
• Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration. [europepmc]
• Growth Factors in Regeneration and Regenerative Medicine: "the Cure and the Cause". [europepmc]
• Complex Tissue Regeneration in Mammals Is Associated With Reduced Inflammatory Cytokines and an Influx of T Cells. [europepmc]
• Metabolic regulation of innate immune cell phenotypes during wound repair and regeneration. [europepmc]
• Appendage Regeneration in Vertebrates: What Makes This Possible? [europepmc]
• Mouse Digit Tip Regeneration Is Mechanical Load Dependent. [europepmc]
• Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine. [europepmc]
• Tissue origin of cytotoxic natural killer cells dictates their differential roles in mouse digit tip regeneration and progenitor cell survival. [europepmc]
• Digit specific denervation does not inhibit mouse digit tip regeneration. [europepmc]
• A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration. [europepmc]
• Macrophages play a key role in tissue repair and regeneration. [europepmc]
• Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration. [europepmc]
• Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche. [europepmc]
• The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration. [europepmc]
• Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse ( Acomys ) ear. [europepmc]
• Enduring questions in regenerative biology and the search for answers. [europepmc]
• Understanding interleukin 11 as a disease gene and therapeutic target. [europepmc]
• The limb dorsoventral axis: Lmx1b's role in development, pathology, evolution, and regeneration. [europepmc]
• Spatiotemporal multi-omics: exploring molecular landscapes in aging and regenerative medicine. [europepmc]
• Spiny mice (Acomys) have evolved cellular features to support regenerative healing. [europepmc]