Does Collective Genetic Regulation exist?

2021/06/29 by J. M. Deutsch, Deutsch, J. M.
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Evolution and Genetic Dynamics #FOS: Biological sciences #Molecular Networks (q-bio.MN) #Populations and Evolution (q-bio.PE)

paper · pdf · doi:10.48550/arxiv.2106.15732

openalex publication_date 2021/06/29 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Does regulation in the genome use collective behavior, similar to the way the brain or deep neural networks operate? Here I make the case for why having a genomic network capable of a high level of computation would be strongly selected for, and suggest how it might arise from biochemical processes that succeed in regulating in a collective manner, very different than the usual way we think about genetic regulation.

Citations

• The perceptron: A probabilistic model for information storage and organization in the brain.
• Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
• The Post-GWAS Era: From Association to Function

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