A 300 bp non-coding repeat sequence has co-evolved with the ced-2/CRKII-set-23/SETMAR genes of nematodes

2025/09/09 by Yeshaswi Pulijala, Victoria E. Brown, Martha Ortega Soto
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Medicine · #Cardiomyopathy and Myosin Studies #Genetics, Aging, and Longevity in Model Organisms #Nematode management and characterization studies

paper · doi:10.17912/micropub.biology.001845

openalex publication_date 2025/09/09 · openalex created_date 2025/10/21 · openalex updated_date 2026/07/01

Abstract

these repeats are more highly conserved than the CED-2 /CRKII coding sequences. These findings suggest the repeats are conserved regulatory modules coordinating CED-2 and SET-23 expression. Supporting this idea, the repeats partially resemble miRNA precursors.

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