2025/04/30 by Heitland, Peter, Göen, Thomas, Hartwig, Andrea +1
#543 Analytical chemistry #543 Analytische Chemie #571.95 Toxicology #571.95 Toxikologie #616.9803 Betriebs- und Arbeitsmedizin #616.9803 Industrial and occupational medicine #Allgemeinbevölkerung #Analysen in biologischem Material #Analysenmethode #Analyses in Biological Materials #Arbeiter #Arbeitnehmer #Arbeitsplatz #Arbeitsplatzbelastung #Biomonitoring #Biomonitoringmethode #Blut #FI-CV-AAS #Fließinjektion-Kaltdampf-Atomabsorptionsspektrometrie #Fließinjektionssystem #HBM #Hintergrundbelastung #Humanbiomonitoring #Intoxikation #Mercury #Mercury compounds #Methode #Methylquecksilber #Quecksilber #Quecksilberverbindungen #Umweltbelastung #Urin #Vergiftung #analytical method #background exposure #biological monitoring #biologisches Monitoring #biomonitoring #biomonitoring method #blood #employee #environmental exposure #flow injection system #flow injection-cold vapour atomic absorption spectrometry #general population #human biomonitoring #intoxication #method #methylmercury #organic #organische #poisoning #urine #worker #workplace #workplace exposure
paper · doi:10.34865/bi743997e2219_w
The working group “Analyses in Biological Materials” of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area validated the presented biomonitoring method. Mercury is determined by flow injection cold vapour atomic absorption spectrometry (CV‐AAS). The digested blood or urine samples are stabilised with potassium permanganate, introduced into the acid carrier flow (hydrochloric acid) and mixed with the reducing agent sodium borohydride. Mercury vapour formed by reduction is transported with an argon flow into the atomisation cell of the AA spectrometer. Calibration is performed using matrix matched calibration solutions. The mercury concentrations in real samples are calculated from the linear relationship between the measured absorbance and the mass concentration of mercury.