2013/04/22 by Bin Ao, Ao, Bin, Sheng Zhang +9
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #FOS: Biological sciences #FOS: Physical sciences #Gene Regulatory Network Analysis #MicroRNA in disease regulation #Molecular Networks (q-bio.MN) #Pattern Formation and Solitons (nlin.PS) #RNA Research and Splicing #nlin.PS #q-bio.MN
paper · pdf · doi:10.48550/arxiv.1304.5836
There were some mistakes in the analysis in this paper's first version submitted on 22 Apr 2013. We corrected them in the second version submitted on 23 Sep 2013. So please delete the "v1" version of this paper, Thank you!
openalex publication_date 2013/04/22 · arxiv created 2013/12/16 · arxiv updated 2013/12/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The dynamic behaviors of microRNA and mRNA under external stress are studied with biological experiments and mathematics models. In this study, we developed a mathematic model to describe the biological phenomenon and for the first time reported that, as responses to external stress, the expression levels of microRNA and mRNA sustained oscillation. And the period of the oscillation is much shorter than several reported transcriptional regulation negative feedback loop.