2014/09/08 by Saurabh Kumar Sharma, Shakti Singh, Sharma, Saurabh Kumar +6
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #FOS: Biological sciences #Gene Regulatory Network Analysis #Molecular Networks (q-bio.MN) #RNA Research and Splicing #q-bio.MN #stochastic dynamics and bifurcation
paper · pdf · doi:10.48550/arxiv.1409.2331
arxiv created 2014/09/08 · openalex publication_date 2014/09/08 · arxiv updated 2014/09/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We study two important roles of miRNA as stress inducer and synchronizing agent in regulating diffusively coupled genetic oscillators within stochastic formalism and competition between them. We identify optimal value of coupling constant at which the rate of synchronization is strongest, below this value sychronizing activity dominates stress activity, and above it stress activity destroys synchronizing pattern. The concentration of miRNA maintained in individual oscillator modulates the synchronization activity achieved by diffusing miRNA.