Premature mortality in autism spectrum disorder
2015/11/06 by Tatja Hirvikoski, Ellenor Mittendorfer-Rutz, Ellenor Mittendorfer‐Rutz +4 · 46 citations
Neuroscience · Medicine · #Autism Spectrum Disorder Research #Child Nutrition and Feeding Issues #Down syndrome and intellectual disability research
paper · pdf · doi:10.1192/bjp.bp.114.160192
Abstract
BACKGROUND: Mortality has been suggested to be increased in autism spectrum disorder (ASD). AIMS: To examine both all-cause and cause-specific mortality in ASD, as well as investigate moderating role of gender and intellectual ability. METHOD: Odds ratios (ORs) were calculated for a population-based cohort of ASD probands (n = 27,122, diagnosed between 1987 and 2009) compared with gender-, age- and county of residence-matched controls (n = 2,672,185). RESULTS: During the observed period, 24,358 (0.91%) individuals in the general population died, whereas the corresponding figure for individuals with ASD was 706 (2.60%; OR = 2.56; 95% CI 2.38-2.76). Cause-specific analyses showed elevated mortality in ASD for almost all analysed diagnostic categories. Mortality and patterns for cause-specific mortality were partly moderated by gender and general intellectual ability. CONCLUSIONS: Premature mortality was markedly increased in ASD owing to a multitude of medical conditions.
Cited by
- Annual Research Review: Shifting from ‘normal science’ to neurodiversity in autism science
- Tackling healthcare access barriers for individuals with autism from diagnosis to adulthood
- Barriers to healthcare and a ‘triple empathy problem’ may lead to adverse outcomes for autistic adults: A qualitative study
- Autism Sensitive Mindfulness-Based Programmes
- Focusing on autism symptoms masks sex-specific needs of autistic children: An example from the Sydney Child Neurodevelopment Research Registry
- The A3ReAcH (Autistic, ADHD and AuDHD research accessibility in healthcare) framework: Principles for inclusive healthcare research with autistic, ADHD and AuDHD individuals in radiography and medical radiation technology
- Defining Neurodiversity Affirming Psychology Practice for Autistic Adults: A Delphi Study Integrating Psychologist and Client Perspectives
- Cannabis and cannabinoid use in autism spectrum disorder: a systematic review
- Adapting Safety Plans for Autistic Adults with Involvement from the Autism Community
- Elevated Suicidal Thoughts and Behaviors and Nonsuicidal Self-Injury in Autistic Youth and Adults: A Multinational Study
- Toward an Emergent Paradigm for Neurodiversity and Health
- Distinguishing midlife and old age: A recommendation for autism researchers
- “Retirement Is One Hell of a Change”: Autistic People's Experiences of Retiring
- Self-harm and Suicidality Experiences of Middle-Age and Older Adults With vs. Without High Autistic Traits
- Autistic SPACE: a novel framework for meeting the needs of autistic people in healthcare settings
- Implementation, Reach, and Safety of Physical Activity Interventions for Autistic Adults: A Scoping Review
- Suicidality in Autistic Adolescents and Adults: Sleep the Unexplored Connection?
- Barriers and Facilitators of Healthcare Access for Autistic Children in the UK: a Systematic Review
- Academic, Activist, or Advocate? Angry, Entangled, and Emerging: A Critical Reflection on Autism Knowledge Production
- Neurodiversity, epistemic injustice, and the good human life
- Neurodiversity‐Affirming Intersectional Approaches That Target Public Policy: Moving the Focus From Changing Individuals to Changing Systems of Power
- Barriers to healthcare: Instrument development and comparison between autistic adults and adults with and without other disabilities. [europepmc]
- The Changing Epidemiology of Autism Spectrum Disorders. [europepmc]
- A Scoping Review of Health Disparities in Autism Spectrum Disorder. [europepmc]
- Autism spectrum disorder. [europepmc]
- Risk markers for suicidality in autistic adults. [europepmc]
- 'People like me don't get support': Autistic adults' experiences of support and treatment for mental health difficulties, self-injury and suicidality. [europepmc]
- The contribution of environmental exposure to the etiology of autism spectrum disorder. [europepmc]
- Understanding the Reasons, Contexts and Costs of Camouflaging for Autistic Adults. [europepmc]
- A 20-year study of suicide death in a statewide autism population. [europepmc]
- Characterizing the Interplay Between Autism Spectrum Disorder and Comorbid Medical Conditions: An Integrative Review. [europepmc]
- Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. [europepmc]
- A Systematic Review of What Barriers and Facilitators Prevent and Enable Physical Healthcare Services Access for Autistic Adults. [europepmc]
- Prevalence of physical and mental health conditions in Medicare-enrolled, autistic older adults. [europepmc]
- Is Camouflaging Autistic Traits Associated with Suicidal Thoughts and Behaviours? Expanding the Interpersonal Psychological Theory of Suicide in an Undergraduate Student Sample. [europepmc]
- Autism spectrum disorder. [europepmc]
- 'I never realised everybody felt as happy as I do when I am around autistic people': A thematic analysis of autistic adults' relationships with autistic and neurotypical friends and family. [europepmc]
- National and State Estimates of Adults with Autism Spectrum Disorder. [europepmc]
- Assessment of Suicidal Behaviors Among Individuals With Autism Spectrum Disorder in Denmark. [europepmc]
- Does Language Matter? Identity-First Versus Person-First Language Use in Autism Research: A Response to Vivanti. [europepmc]
- Genetic contributions to autism spectrum disorder. [europepmc]
- Tackling healthcare access barriers for individuals with autism from diagnosis to adulthood. [europepmc]
- Prevalence of Autism Spectrum Disorder and Co-morbidities in Children and Adolescents: A Systematic Literature Review. [europepmc]
- Mortality in Persons With Autism Spectrum Disorder or Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis. [europepmc]
- Sex and gender in neurodevelopmental conditions. [europepmc]
- The Autism Spectrum: Behavioral, Psychiatric and Genetic Associations. [europepmc]
Related