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Trimethylamine

2025/01/01 by Hartwig, Andrea, MAK Commission
Biochemistry, Genetics and Molecular Biology · Environmental Science · Medicine · #571.95 Toxicology #571.95 Toxikologie #616.9803 Betriebs- und Arbeitsmedizin #616.9803 Industrial and occupational medicine #Carcinogens and Genotoxicity Assessment #Indoor Air Quality and Microbial Exposure #Luft #MAK value #MAK-Wert #Momentanwert #N #N-Dimethylmethanamin #N-Dimethylmethanamine #Nasenepithel #Occupational exposure and asthma #Reizwirkung #Spitzenbegrenzung #TMA #Trimethylamin #Trimethylamine #air #ceiling limit value #irritation #maximale Arbeitsplatzkonzentration #maximum workplace concentration #momentary value #nasal epithelium #peak limitation

paper · doi:10.34865/mb7550e6518_w

openalex publication_date 2025/01/01 · openalex created_date 2025/12/13 · openalex updated_date 2026/07/01

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated a momentary value for trimethylamine [75‐50‐3]. Critical effect is the irritation of the respiratory epithelia in the nose of rats and a maximum concentration at the workplace (MAK value) of 2 ml/m3 has been set. This value was established by analogy with cyclohexylamine. In addition to the MAK value, a momentary value of 5 ml/m3 for cyclohexylamine has been established which must not be exceeded at any time to prevent from local irritation. Therefore, a momentary value of 5 ml/m3 is also set for N,N‐trimethylamine.

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