Platelet GPIb: sensing force and responding

2015/01/15 by Zaverio M. Ruggeri · 9 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Chronic Lymphocytic Leukemia Research #Platelet Disorders and Treatments #PI3K/AKT/mTOR signaling in cancer

paper · pdf · doi:10.1182/blood-2014-12-610642

Abstract

growth factor b inhibitors as a therapeutic option.

Cited by

• From haemostasis to immunity: The expanding frontiers of platelet biology
• Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals. [europepmc]
• Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species. [europepmc]
• [Platelet GPⅠb-Ⅸ-Ⅴ receptor-mediated mechanism and its application in thrombotic diseases]. [europepmc]
• From Classical to Unconventional: The Immune Receptors Facilitating Platelet Responses to Infection and Inflammation. [europepmc]
• Soy Isoflavones Inhibit Both GPIb-IX Signaling and αIIbβ3 Outside-In Signaling via 14-3-3ζ in Platelet. [europepmc]
• Why platelet mechanotransduction matters for hemostasis and thrombosis. [europepmc]
• Harnessing the power of bioprinting for the development of next-generation models of thrombosis. [europepmc]
• Blood Mechanical Intelligence: From Force Sensing to Precision Mechanomedicine. [europepmc]

Related

• Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation
• Role of platelet-derived growth factors in physiology and medicine
• Activation of Platelet Function Through G Protein–Coupled Receptors
• REGULATION OF PLATELET FUNCTIONS BY P2 RECEPTORS
• Platelet-rich Plasmas: Growth Factor Content and Roles in Wound Healing